2015年起任科技部重点研发计划“蛋白质机器与生命过程调控”重点专项指南编写专家组成员,

2017年起任科技部重点研发计划总体专家组成员。

2017年任中国晶体学会副监事长和中国生物化学与分子生物学学会监事。

1、蓝藻水华形成和的分子机理和干预策略

2、噬藻体组装和特异性侵染宿主的分子机制

3、蓝藻碳氮代谢平衡调控的分子机理

(1) Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate. - Proc Natl Acad Sci USA. - 2010 - 107(28)

(2) Neofunctionalization of zona pellucida proteins enhances freeze-prevention in the eggs of Antarctic notothenioids - Nature Communications - - 2041-1723

(3) Structural Insights into SraP-Mediated Staphylococcus aureus Adhesion to Host Cells - PLoS Pathogens - - 1553-7366

(4) Structures of yeast glutathione S-transferase Gtt2 reveal a new catalytic type of GST family - EMBO Reports - 2009 -

(5) Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein - EMBO REPORTS - - 1469-221X

(6) Structures of an all-α protein running along the DNA major groove - NUCLEIC ACIDS RESEARCH - - 0305-1048

(7) Crystal structure and computational analyses provide insights into the catalytic mechanism of 2, 4-diacetylphloroglucinol hydrolase PhlG from Pseudomonas fluorescens. - J Biol Chem. - 2010 - 285(7)

(8) Structural plasticity of the thioredoxin recognition site of yeast methionine-S-sulfoxide reductase Mxr1 - JOURNAL OF BIOLOGICAL CHEMISTRY - - 0021-9258

(9) Recognition of the Thomsen-Friedenreich Pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor - JOURNAL OF BIOLOGICAL CHEMISTRY - - 0021-9258

(10) Structure and Catalytic Mechanism of Yeast 4-Amino-4-deoxychorismate Lyase - JOURNAL OF BIOLOGICAL CHEMISTRY - - 0021-9258

(11) Crystal Structure of the Cyanobacterial Signal Transduction Protein P(II) in Complex with PipX - JOURNAL OF MOLECULAR BIOLOGY - - 0022-2836

(12) Structural and biochemical characterization of yeast monothiol glutaredoxin Grx6. - J Mol Biol. - 2010 - 398(4)

(13) Crystal structure of cyanobacterial signal transduction protein PII in complex with PipX. - J Mol Biol. - 2010 -

(14) Systematic cloning and analysis of autophagy-related genes from the silkworm Bombyx mori - BMC Mol Biol. - 2009 -

(15) Crystal structure of Saccharomyces cerevisiae glutamine synthetase Gln1 suggests a nanotube-like supramolecular assembly - Proteins - 2009 -

(16) Structural basis for the unique anti-tumor activity of LZ-8 from the fungus Ganoderma lucidium - Proteins - 2009 -

(17) Crystal structure of the dimeric Urm1 from the yeast Saccharomyces cerevisiae - Proteins - 2008 -

(18) Crystal structure of glutathione-dependent phospholipid peroxidase Hyr1 from the yeast Saccharomyces cerevisiae - Proteins - 2008 - 73

(19) Glutathionylation-triggered conformational changes of glutaredoxin Grx1 from the yeast Saccharomyces cerevisiae. - Proteins - 2008 -

(20) Crystal structure of the yeast cytoplasmic thioredoxin Trx2. - Proteins - 2007 -

(21) Crystal structure of glutathione reductase Glrl from the yeast Saccharomyces cerevisiae - Proteins - 2007 -

(22) Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1 - BMC Struct Biol. - 2007 -

(23) The gene expression profile of Bombyx mori silkgland - Gene - 2007 -

(24) Solution structure and metal binding properties of Kti11p from Saccharomyces cerevisiae - Biochemistry - 2005 -

(25) Developments in structural genomics:protein purification and function interpertation. - Current Genomics - 2004 -

(26) The 62-kb upstream region of Bombyx mori fibroin heavy chain gene is clustered of erpetitive element - GENE - 2003 -

(27) Crystal structure of the yeast PX-domain protein Grd19p complexed to phosphatidyl-inositol-3-ph osph - J Biol Chem. - 2003 -

(28) Silk fibroin:Structural implications of a remarkable amino acid sequence(SCI) - PROTEINS - 2001 -

(29) Identification and characterization of a silkgland-related matrix association ergion in Bombyx mori - Gene - 2001 -

(30) Fine organization of Bombyx mori fibroin heavy chain gene(SCI) - Nucleic Acids Research - 2000 -