沈薇

更新时间:2022-01-14 03:14

沈薇,女,江苏科技大学教授,硕士生导师,博士。2011年本科毕业于浙江大学,2016年博士毕业于新加坡国立大学,2016年7月就职于江苏科技大学。

人物经历

理学博士, 2011.08~2016.02,新加坡国立大学分析化学专业

理学学士, 2007.08~2011.06,浙江大学(化学专业)

2016.07~,江苏科技大学工作

研究方向

(1)微RNA灵敏分析检测

(2)纳米材料合成及分析应用

(3)DNA单核苷酸多态性分析检测

(4)文物保护与文物分析检测

课程教学

(1)化学工艺(硕士研究生)

(2)仪器分析(本科生)

(3)现代仪器分析(硕士研究生,双语)

(4)Modern Analysis and Testing Technology(留学硕士研究生,全英文)

(5)分析化学(本科生)

主要贡献

科研项目

(1)基于等温循环信号放大的多通路同时检测多种微RNA的分析方法,国家自然科学基金青年基金。(主持)

(2)靶向钌配合物功能化金纳米粒子复合体系的构建及其荧光成像研究,国家自然科学基金面上项目。(参与)

(3)基于信号放大的高效检测多种疾病相关微RNA的分析检测,江苏科技大学引进人才启动基金。(主持)

(4)Ultrasensitive biosensors, A*STAR-ANR 。(参与)

(5)Developing new microfluidic chambers for cancer cell screening, A*STAR-ANR。(参与)

(6)Ultrasensitive and label-free assays,A*STAR-ANR。(参与)

(7)仿细胞结构水滑石材料的合成及其对肽类激素的萃取性能研究,国家自然科学基金青年基金。(参与)

(8)江苏省“双创计划”。(主持)

(9)江苏省“六大人才高峰”高层次人才项目。(主持)

(10) 江苏科技大学“青年学者计划”第二层次。(主持)

论文著作

[1] W. Shen, H. Deng, Z. Gao, Gold nanoparticle-enabled real-time ligation chain reaction for ultrasensitive detection of DNA, J. Am. Chem. Soc. 134 (2012) 14678-14681.

[2] W. Shen, H. Deng, Y. Ren, Z. Gao, A label-free microRNA biosensor based on DNAzyme-catalyzed and microRNA-guided formation of a thin insulating polymer film, Biosens. Bioelectron. 44 (2013) 171-176.

[3] W. Shen, H. Deng, Y. Ren, Z. Gao, An electronic sensor array for label-free detection of single-nucleotide polymorphisms, Biosens. Bioelectron. 43 (2013) 165-172.

[4] W. Shen, Z. Gao, Quantum dots and duplex-specific nuclease enabled ultrasensitive detection and serotyping of Dengue viruses in one step in a single tube, Biosens. Bioelectron. 65 (2015) 327-332.

[5] W. Shen, H. Deng, A.K.L. Teo, Z. Gao, Colorimetric detection of single-nucleotide polymorphisms with a real-time PCR-like sensitivity, Chem. Commun. 48 (2012) 10225-10227.

[6] W. Shen, H. Deng, Y. Ren, Z. Gao, A real-time colorimetric assay for label-free detection of microRNAs down to sub-femtomolar levels, Chem. Commun. 49 (2013) 4959-4961.

[7] W. Shen, C.L. Lim, Z. Gao, A ferrofluid-based homogeneous assay for highly sensitive and selective detection of single-nucleotide polymorphisms, Chem. Commun. 49 (2013) 8114-8116.

[8] W. Shen, H. Deng, A.K.L. Teo, Z. Gao, An electrodeposited redox polymer-laccase composite film for highly efficient four-electron oxygen reduction, J. Power Sources 226 (2013) 27-32.

[9] W. Shen, Y. Tian, T. Ran, Z. Gao, Genotyping and quantification techniques for single-nucleotide polymorphisms, TrAC, Trends Anal. Chem. 69 (2015) 1-13.

[10] W. Shen, K.H. Yeo, Z. Gao, A simple and highly sensitive fluorescence assay for microRNAs, Analyst 140 (2015) 1932-1938.

[11] W. Shen, H. Deng, Z. Gao, Synthesis of polyaniline via DNAzyme-catalyzed polymerization of aniline, RSC Adv. 4 (2014) 53257-53264.

[12] W. Shen, H. Deng, Z. Gao, Synthesis and anticancer properties of a novel bis-intercalator, Anti-Cancer Agents Med. Chem. 13 (2013) 632-638.

[13] S.Y. Lim, W. Shen, Z. Gao, Carbon quantum dots and their applications, Chem. Soc. Rev. 44 (2015) 362-381.

[14] H. Deng, W. Shen, Y. Ren, Z. Gao, A highly sensitive and selective homogenous assay for profiling microRNA expression, Biosens. Bioelectron. 54 (2014) 650-655.

[15] H. Deng, W. Shen, Y. Ren, Z. Gao, A highly sensitive microRNA biosensor based on hybridized microRNA-guided deposition of polyaniline, Biosens. Bioelectron. 60 (2014) 195-200.

[16] H. Deng, W. Shen, Z. Gao, Colorimetric detection of single nucleotide polymorphisms in the presence of 103-fold excess of a wild-type gene, Biosens. Bioelectron. 68 (2015) 310-315.

[17] Z. Gao, W. Shen, H. Deng, Y. Ren, Detection of single-nucleotide polymorphisms based on the formation of an electron-transfer impeding layer on an electrode surface, Chem. Commun. 49 (2013) 370-372.

[18] H. Deng, W. Shen, Z. Gao, Synthesis of water-soluble and cross-linkable ferrocenyl redox polymers for uses as mediators in biosensors, Sens. Actuators, B 168 (2012) 238-242.

[19] H. Deng, Y. Ren, W. Shen, Z. Gao, An ultrasensitive homogeneous chemiluminescent assay for microRNAs, Chem. Commun. 49 (2013) 9401-9403.

[20] Y. Ren, H. Deng, W. Shen, Z. Gao, A Highly Sensitive and Selective Electrochemical Biosensor for Direct Detection of MicroRNAs in Serum, Anal. Chem. 85 (2013) 4784-4789.

[21] Z. Gao, H. Deng, W. Shen, Y. Ren, A Label-Free Biosensor for Electrochemical Detection of Femtomolar MicroRNAs, Anal. Chem. 85 (2013) 1624-1630.

[22] Y. Yu, Y. Ren, W. Shen, H. Deng, Z. Gao, Applications of metal-organic frameworks as stationary phases in chromatography, TrAC, Trends Anal. Chem. 50 (2013) 33-41.

[23] H. Deng, W. Shen, Y. Peng, X. Chen, G. Yi, Z. Gao, Nanoparticulate Peroxidase/Catalase Mimetic and Its Application, Chem. - Eur. J. 18 (2012) 8906-8911.

[24] F. Xu, D. Huang, C. Han, W. Shen, X. Lin, Y. Wang, SPINOL-derived phosphoric acids: synthesis and application in enantioselective Friedel− Crafts reaction of indoles with imines, J. Org. Chem. 75 (2010) 8677-868.

[25] H. Deng, W. Shen, Z. Gao, An Interference-Free Glucose Biosensor Based on an Anionic Redox Polymer-Mediated Enzymatic Oxidation of Glucose, ChemPhysChem 14 (2013) 2343-2347.

[26] H. Zhang, M. Shi, W. Shen, Z. Li, B. Zhang, R. Liu, R. Zhang, Damage or protection? The role of smoked crust on sandstones from Yungang Grottoes, J. Archaeol. Sci. 40 (2013) 935-942.

[27] S. Tang, Y. Chang, W. Shen, H. K. Lee, Selective extraction by dissolvable (nitriloacetic acid-nickel)-layered double hydroxide coupled with reaction with potassium thiocyanate for sensitive detection of iron (III), Talanta 154 (2016) 416-422.

[28] L. Liu, W. Shen, B. Zhang, Y. Han, Determination of proteinaceous binders for polychrome relics of Xumi mountain grottoes by using enzyme-linked immunosorbent assay and immunofluorescence microscopy, Inter. J. Conserv. Sci. 7 (2016) 3-14.

[29] L. Liu, W. Shen, B. Zhang, Q. Ma, Microchemical study of pigments and binders in polychrome relics from Maiji Mountain Grottoes in northwestern China, Microsc. Microanal. 22 (2016) 845-856.

[30] S. Tang, J. Sun, Y. Li, D. Xia, T. Qi, K. Liu, H. Deng, W. Shen*, H.K. Lee, pH-dependent selective ion exchange based on (EDTA-nickel)-layered double hydroxide to catalyze the polymerization of aniline for detection of Cu2+ and Fe3+, Talanta 187 (2018)287-294.

[31] J. Sun, Y. Li, C. Chen, T. Qi, D. Xia, W. Mao, T. Yang, L. Chen, W. Shen*, S. Tang*, Magnetic Ni/Fe layered double hydroxides nanosheets as enhancer for DNA hairpin sensitive detection of miRNA. Talanta 187(2018)265-271.

[32] W. Shen, Y. Li, T. Qi, S. Wang, J. Sun, H. Deng, H. Lu, C. Chen, L. Chen, Sheng Tang, Fluorometric determination of zinc(II) by using DNAzyme-modified magnetic microbeads, Microchimica Acta 185(2018) 447.

[33] S. Tang, T. Qi, P. D. Ansah, J. C. N. Fouemina, W. Shen, C. Basheer, Kee Hian Lee*, Single drop Microextraction,TrAC Trends in Analytical Chemistry, 108(2018) 306-313.

[34] Shen Wei, Sun Jun, Shi Lei, Tang Sheng*, Lee Hian Kee*. Needle-based sampling coupled with colorimetric reaction catalyzed by layered double hydroxide peroxidase mimic for rapid detection of the change of D-glucosed level in banana. Analytica Chimica Acta 1001 (2018) 845-856.

[35] Tang Sheng*, Sun Jun, Xia Dasha, Zang Bin, Gao Yuhua, Chen Chuanxiang*, Shen Wei, Lee Hian Kee*, In-syringe extraction using compressible and self-recoverable, amphiphilic graphene aerogel as sorbent for determination of phenols. Talanta 195(2019) 165-172.

[36] Deng Huimin, Tang Gangling, Fan Ziyan, Liu Shanshan, Li Zhonghao, Wang Ying, Bian Zhaoyang, Shen Wei, Tang Sheng*, Yang Fei*, Use of autoclave extraction-supercritical fluid chromatography/tandem mass spectrometry to analyze 4-(methylintrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine in tobacco, Journal of Chromatography A1595(2019) 207-214.

[37] Tang Sheng*, Li Yana, Zhu Anni, Yao Yao, Sun Jun, Zheng Fenfen, Lin Zixia, Shen Wei*, A triple-amplification strategy based on the formation of peroxidase-like two dimensional DNA/Fe3O4 networks initiated by hybridization chain reaction for highly sensitive detection of microRNA, Chemical Communications, 55 (2019) 8386-8389.

[38] Li Yana, Sun Jun, Mao Wei, Tang Sheng*, Liu Kai, Qi Tong, Deng Huimin, Shen Wei*, Chen Lizhuang, Peng Luming, Antimony doped tin oxide nanoparticles as peroxidase mimics for paper-based colorimetric detection of glucose using smartphone read-out, Microchimica Acta, 186 (2019) 403.

[39] Tang Sheng*, Qi Tong, Xia Dasha, Xu Mengchan, Xu Mengyuan, Zhu Anni, Shen Wei, Lee Hian Kee*, Smartphone nanocolorimetric determination of hydrogen sulfide in biosamples after silver-gold core-shell nanoprism-based headspace single drop microextraction, Analytical Chemistry, 91 (2019) 5888-5895.

[40] Tang Sheng*, Xia Dasha, Yao Yao, Chen Tianyu, Sun Jun, Yin Yijie, Shen Wei, Peng Yinxian, Dye adsorption by self-recoverable, adjustable amphiphilic graphene aerogel, Journal of Colloid and Interface Science, 554 (2019) 682-691.

[41] Tang Sheng*, Yao Yao, Chen Tianyu, Kong Dezhao, Shen Wei, Lee Hian Kee, Recent advances in the application of layered double hydroxides in analytical chemistry: A review, Analytica Chimica Acta, 1103 (2020) 32-48. Invited review.

[42] I. D. Tegladza, T. Qi, T. Chen, K. Alorku,S. Tang*, W. Shen*, D. Kong, A. Yuan, J. Liu, H. K. Lee*, Direct immersion single-drop microextraction of semi-volatile organic compounds in environmental samples: A review, J. Hazard. Mater. 393 (2020) 122403.

[43] Z. Li, C. Zhang, F. Han*, F. Wang, F. Zhang, W. Shen, C. Ye, X. Li, J. Liu*, Towards high-volumetric performance of Na/Li-ion batteries: a better anode material with molybdenum pentachloride–graphite intercalation compounds (MoCl5–GICs), J. Mater. Chem. A 8 (2020) 2430-2438.

[44] T. Qi, C. Song, J. He, W. Shen*, D. Kong, H. Shi, L.Tan, R. Pan, S. Tang*, H. K. Lee*, Highly Sensitive Detection of Multiple MicroRNAs by High-Performance Liquid Chromatography Coupled with Long and Short Probe-based Recycling Amplification, Anal. Chem. 2020, Accepted.DOI: 10.1021/acs.analchem.9b05301.

获奖记录

(1)国家优秀自费留学生奖学金,2015年

(2)新加坡国立大学总统奖学金,2014年

(3)新加坡国立大学理学院研究生最佳科研奖,2013年

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