更新时间:2021-02-01 19:00
韩东,研究员,博士生导师。1998年在中国中医研究院(现更名为中国中医科学院)获中西医结合血液学临床医学硕士学位,2001年获中西医结合血液学基础医学博士学位。之后在清华大学物理系、香港浸会大学中医药学院、法国巴黎高等师范学院化学系从事博士后,访问及高级访问学者研究工作。2004年3月进入国家纳米科学中心工作。现任国际临床血液流变学会国际联络员,中国病理生理学会微循环专业委员会当选副秘书长,中国生物物理学会生物力与生物流变专业委员会委员、中国中西医结合学会微循环专业委员会委员、中国病理生理学会休克专业委员会当选委员。
纳米生物医学成像与表征,生物医学工程,生物力药理学。以原子力显微镜、环境扫描电镜为平台,特色应用及发展纳米成像、表征、操纵及微加工集成设备功能群,研究生物医学关键问题;生物活体功能界面“微尺度构建-功能-力学偶联”相关机制研究。
1. Liang Shi, Shenggen Shi, Jing Li, Quanmei Sun, Peipei Chen, Long Chen and Dong Han*.AFM and fluorescence imaging of nanomechanical response in periodontal ligament cells. Front. Biosci. 2010, Online.
2.Long Chen, Weiguo Chu, Yonggang Xu, Peipei Chen, Fang Lao, Quanmei Sun, Xizeng Feng and Dong Han*. Time-series investigation of fused vesicles in microvessel endothelial cells with atomic force microscopy. Microsc. Res. Techniq. 2010, 73, 152-159.
3. Liping Heng, Dongliang Tian, Long Chen, Junxin Su, Jin Zhai*, Dong Han* and Lei Jiang. Local photoelectric conversion properties of the titanyl-phthalocyanine (TiOPc) coated aligned ZnO nanorodsw. Chem Comm. 2010,46,1162.
4. Li Chen, Mingjie Liu, Hao Bai, Peipei Chen, Fan Xia, Dong Han* and Lei Jiang*.Antiplatelet and thermally responsive poly(N-isopropylacrylamide) surface by with nanoscale topography. J. Am. Chem. Soc. 2009, 131, 10467-10472 (Article).
5. Honglei Fan, Peipei Chen, Ruomei Qi, Jin Zhai, Jingxia Wang, Long Chen, Li Chen, Quanmei Sun, Yanlin Song, Dong Han* and Lei Jiang*. Largely improve blood-compatibility by microscopic multi-scale design of surface architectures. Small. 2009, 5, 2144-2148 (Highlighted by Nature Nanotechnology).
6. Fang Lao, Long Chen, Wei Li, Cuicui Ge, Ying Qu, Quanmei Sun, Yuliang Zhao, Dong Han* and Chunying Chen*.Fullerene nanoparticles selectively enter oxidation-damaged cerebral microvessel endothelial cells and inhibit JNK-related apoptosis. ACS NANO. 2009,3,3358-3368 (Article).
7.Peipei Chen, Hongtao Dong, Long Chen, Quanmei Sun and Dong Han*. The application of atomic force microscopy on living samples, from cells to fresh tissues. Chinese Sci.Bull. 2009, 54, 2410-2415 (Review).
8.Youdong Mao, Quanmei Sun, Xiufeng Wang, Qi Ouyang, Li Han, Lei Jiang* and Dong Han*. In vivo nanomechanical imaging of blood-vessel tissues directly in living mammals using atomic force microscopy. Appl. Phys. Lett. 2009,95,013704.
9.Peipei Chen, Long Chen, Dong Han*, Jin Zhai, Yongmei Zheng and Lei Jiang*. Wetting behavior at micro-/nanoscales: direct imaging of a microscopic water/air/solid three-phase interface. Small. 2009, 5, 908-912 (Inside Cover Picture).
10. Guanglu Ge, Dong Han*, Danying Lin, Weiguo Chu, Yunxu Sun, Lei Jiang, Wanyun Ma and Chen Wang. MAC mode atomic force microscopy studies of living samples, ranging from cells to fresh tissue. Ultramicroscopy. 2007, 107, 299-307.
11. Wanyun Ma, Yunxu Sun, Dong Han *, Weiguo Chu, Danying Lin and Dieyan Chen. Cytoskeletal response of microvessel endothelial cells to an applied stress force at the submicrometer scale studied by atomic force microscopy. Microsc. Res. Techniq. 2006, 69, 784-793.
金属纳米粒子生物效应的环境扫描电子显微镜检测方法通则。第一起草人。
纳米粒子生物效应研究中活体生物样本的磁驱动轻敲模式原子力显微镜检测方法通则。第一起草人。
2002年获国际生物流变学会颁发的第一届“Chien-Fung Award”,奖励1名有突出成绩的中国青年生物力学工作者。2008年获日本显微镜学会颁发的年度生物医学论文奖。