更新时间:2024-07-08 10:15
王佳伟,男, 1976年11月出生,研究员,现任中国科学院分子植物科学卓越创新中心副主任。2022年,入选谈家桢生命科学创新奖候选名单。
1995-09--1999-06 上海交通大学 学士
1999-09--2005-08 上海生命科学研究院 博士
2005-08~2011-07,Max Planck Institute for Developmental Biology, 博士后
2011-08~2020-01,上海生命科学研究院植物生理生态研究所, 研究员
2020-01~现在, 中国科学院分子植物科学卓越创新中心, 研究员
2019-10~现在, 中国科学院分子植物科学卓越创新中心, 副主任
2022年,入选谈家桢生命科学创新奖候选名单。
植物时序性发育和生命周期
实验室以一年生草本植物--拟南芥(Arabidopsis thaliana)和十字花科多年生草本植物为模式,利用遗传学,反向遗传学、单细胞测序和细胞谱系追踪技术,回答如下一些科学问题:
1)植物如何从一个单细胞合子通过细胞分裂和分化发育成为一个多细胞的个体;
2)年龄不可逆的分子机理;
3)年龄如何调控植物再生能力和干细胞基因组的稳定性;
4)植物生活习性自然变异的遗传学基础;
5)多年生植物生活习性及其干细胞长久维持的分子机理。
2012 Excellent Young Scholars, NSFC, CHINA
2013 明治生命科学奖
2014 中国科学院上海分院第四届杰出青年科技创新人才奖
2015 Outstanding Academic Leaders Award, SHANGHAI, CHINA
2015 国家杰出青年基金
2016 Young Talents Award in Science & Technology, SHANGHAI, CHINA
2016 Science & Technology Award for Young and Middle-aged Talents, CHINA
2017 Leading Talents Award in Science & Technology, MOST, CHINA
2022年9月15日,荣获2022年科学探索奖(生命科学)。
2022年12月,获得第十五届谈家桢生命科学创新奖。
2023年10月,第二期新基石研究员。
河南大学《科学前沿》讲座
南京农业大学《科学前沿进展报告》
植物生理与分子生物学
复旦大学《植物遗传与发育》
( 1 ) 植物激素与年龄途径整合的分子机理, 负责人, 国家任务, 2013-01--2015-12
( 2 ) 植物小分子RNA的生物学功能, 负责人, 国家任务, 2013-01--2015-12
( 3 ) 植物年龄途径的分子解析, 负责人, 国家任务, 2015-01--2019-12
( 4 ) 植物小分子RNA与年龄途径, 负责人, 国家任务, 2016-01--2020-12
( 5 ) 高等植物开花时间多样性的分子机理, 参与, 国家任务, 2018-01--2024-12
( 6 ) 未来作物分子设计, 参与, 国家任务, 2018-01--2023-12
( 7 ) MIR156/7调控一年生和多年生植物成花诱导的分子机理, 负责人, 国家任务, 2018-01--2020-12
1. Wu LY#, Shang GD#, Wang FX, Gao J, Wan MC, Xu ZG, and Wang JW*. (2022). Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration. Dev Cell.
2. Huang K#, Wu XX#, Fang CL#, Xu ZG#, Zhang HW, Gao J, Zhou CM, You LL, Gu ZX, Mu WH, Feng Y*, Wang JW*, and Zhang Y*. (2021). Pol IV and RDR2: a two-RNA-polymerase machine that produces double-stranded RNA. Science. 374(6575): 1579-1586.
3. Cheng YJ, Shang GD, Xu ZG, Yu S, Wu LY, Zhai D, Tian SL, Gao J, Wang L, and Wang JW*. (2021). Cell division in the shoot apical meristem is a trigger for miR156 decline and vegetative phase transition in Arabidopsis. PNAS. 118(46): e2115667118.
4. Zhang TQ, Chen Y, Liu Y, and Wang JW*. (2021). Single-cell transcriptome atlas and chromatin accessibility landscape reveal differentiation trajectories in the rice root. Nat Commun. 12: 2053.
5. Zhang TQ, Chen Y, and Wang JW*. (2021). A single-cell analysis of the Arabidopsis vegetative shoot apex. Dev Cell. 56(7): 1056-1074.
6. Lian H, Wang L, Ma N, Zhou CM, Han L, Zhang TQ, and Wang JW*. (2021). Redundant and specific roles of individual MIR172 genes in plant development. PLOS Biol. 19(2): e3001044.
7. Wang FX#, Shang GD#, Wu LY, Xu ZG, Zhao XY, and Wang JW*. (2020). Chromatin accessibility dynamics and a hierarchical structure of transcriptional regulatory network for plant somatic embryogenesis. Dev Cell. 54(6): 742-757.
8. Ye BB, Shang GD, Pan Y, Xu ZG, Zhou CM, Mao YB, Bao N, Sun L, Xu T, and Wang JW*. (2020). AP2/ERF transcription factors integrate age and wound signals for root regeneration. Plant Cell. 32(1): 226-241.
9. Wang L#, Zhou CM#, Mai YX, Li LZ, Gao J, Shang GD, Lian H, Han L, Zhang TQ, Tang HB, Ren H, Wang FX, Wu LY, Liu XL, Wang CS, Chen EW, Zhang XN, Liu C, and Wang JW*. (2019). A spatiotemporally regulated transcriptional complex underlies heteroblastic development of leaf hairs in Arabidopsis thaliana. EMBO J. 38(8): 100063.
10. Zhang TQ#, Xu ZG#, Shang GD, and Wang JW*. (2019). A single-cell RNA sequencing profiles the developmental landscape of Arabidopsis root. Mol Plant. 12(5): 648-660.
11. Zhang TQ, Lian H, Zhou CM, Xu L, Jiao YL, and Wang JW*. (2017). A two-step model for de novo activation of WUSCHEL during plant shoot regeneration. Plant Cell. 29(5): 1073-1087.
12. Yu S, Lian H, and Wang JW*. (2015). Plant developmental transitions: the role of microRNAs and sugars. Curr Opin Plant Biol. 27: 1-7. (invited review)
13. Zhang TQ, Lian H, Tang H, Dolezal K, Zhou CM, Yu S, Chen JH, Chen Q, Liu H, Ljung K, and Wang JW*. (2015). An intrinsic microRNA timer regulates progressive decline in shoot regenerative capacity in plants. Plant Cell. 27(2): 349-360.
14. Rubio-Somoza I, Zhou CM, Confraria A, Martinho C, Born P, Baena-Gonzalez E, Wang JW*, and Weigel D*. (2014). Temporal control of leaf complexity by miRNA-regulated licensing of protein complexes. Curr Biol. 24(22): 2714-2719.
15. Zhou CM, Zhang TQ, Wang X, Yu S, Lian H, Tang H, Feng ZY, Zozomova-Lihova J, and Wang JW*. (2013). Molecular basis of age-dependent vernalization in Cardamine flexuosa. Science. 340(6136): 1097-1100.
16. Yu S, Cao L, Zhou CM, Zhang TQ, Lian H, Sun Y, Wu JQ, Huang JR, Wang GD, and Wang JW*. (2013). Sugar is an endogenous cue for juvenile-to-adult phase transition in plants. eLife. 2: e00269.
17. Yu S#, Galvao V#, Zhang YC, Horrer D, Zhang TQ, Hao YH, Feng YQ, Wang S, Schmid M, and Wang JW*. (2012). Gibberellin regulates Arabidopsis floral transition through miR156-targeted SQUAMOSA PROMOTER BINDING-LIKE transcription factors. Plant Cell. 24(8): 3320-3332.
18. Gou JY, Felipes FF, Liu CJ, Weigel D, and Wang JW*. (2011). Negative Regulation of anthocyanin biosynthesis in Arabidopsis by a miR156-targeted SPL transcription factor. Plant Cell. 23(4): 1512-1522.
19. Wang JW*#, Park MY#, Wang LJ, Chen XY, Weigel D, and Poethig S*. (2011). MiRNA Control of Vegetative Phase Change in Trees. PLOS Genet. 7: e1002012.